Updated July 2026 · 8 min read
Cats are obligate predators who evolved to hide illness and weakness. In the wild, showing vulnerability invites predation. In your home, this means a sick cat will often act normally until a disease is significantly advanced. Active monitoring — noticing changes before they become obvious — is the most effective tool cat owners have.
Is your cat eating? Complete food refusal for more than 24-36 hours in a cat is always a reason to call the vet — cats who don't eat develop hepatic lipidosis (fatty liver disease) faster than any other domestic animal.
Is your cat drinking? Most cats drink less than you'd expect (they evolved to get moisture from prey). Increased drinking (polydipsia) is one of the earliest signs of kidney disease, diabetes, and hyperthyroidism — the three most common serious feline diseases. If you notice your cat visiting the water bowl more, note it with a date.
Did they use the litter box? Monitoring output is most easily done with a single litter box (rather than multiple). A cat that hasn't urinated in 24+ hours may have a urinary blockage — a life-threatening emergency in male cats especially.
Weight: A bathroom scale with you holding the cat works fine. Track the number monthly. A 0.5 lb loss in a 10 lb cat is a 5% body weight loss — medically significant. Cats lose weight slowly from chronic disease, and owners often attribute it to "aging" when it's something treatable.
Coat quality: A healthy cat's coat is smooth, consistent, and sheds moderately. A dull, clumped, or unkempt coat often indicates pain (the cat can't groom normally), dental disease, or arthritis. Cats that stop grooming their back half are often experiencing spinal or hip pain.
Eyes and ears: Eyes should be clear without discharge or squinting. Pawing at one ear, head shaking, or dark discharge in the ear canal suggests an ear infection or mites.
Sudden hiding or behavioral change. Straining in the litter box without producing urine. Breathing with mouth open (cats almost never pant). Vomiting more than twice in 24 hours or blood in vomit. Limping that doesn't resolve in 24-48 hours. Rapid breathing at rest. Third eyelid (white membrane) visible at the corner of the eye.
Keep a simple log: monthly weight, quarterly coat/mobility observations, any vet visits with dates and findings. When something changes, you have a documented baseline to compare against rather than guessing whether your cat has "always been this way" or whether something shifted. This record also makes vet appointments more efficient — "she lost 0.4 lbs since my last note four weeks ago" is more clinically useful than "she seems thinner lately."
Get The ICU Notebook Newsletter
Clinical tools and career insights for ICU nurses. One email per week, no fluff.
Yes, send it freeNo spam. Unsubscribe any time.