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Earn $300k–$480k working assignments on your schedule — the complete guide for CRNAs
Locum tenens is the highest-paying arrangement available in the CRNA profession. While a staff CRNA averages $195,000–$235,000 annually, experienced locum CRNAs regularly clear $300,000–$480,000 — working the same number of hours, often fewer.
The math is simple: you trade the security of a W-2 position for premium per-diem rates, tax advantages unique to independent contractors, and the ability to choose your assignments. For experienced CRNAs who have paid off their student loans and built a financial foundation, locums is the wealth acceleration play most of the profession underutilizes.
Locum tenens (Latin: "one holding a place") means working temporary assignments at hospitals, surgery centers, and clinics that need CRNA coverage. You contract through a locum agency, work the agreed schedule, and move on. There's no PTO, no office politics, no mandatory committee work, and no 5-year career ladder.
A typical CRNA locum assignment:
| Setting | Typical Rate | Annual Equivalent (48 weeks) |
|---|---|---|
| Urban hospital OR | $175–$200/hr | $336k–$384k |
| Rural critical access hospital | $200–$240/hr | $384k–$460k |
| Outpatient surgery center | $160–$185/hr | $307k–$355k |
| Pain management clinic | $155–$180/hr | $298k–$346k |
| OB anesthesia (24hr coverage) | $185–$225/hr | $355k–$432k |
| Trauma Level I (high-acuity locum) | $220–$260/hr | $422k–$499k |
Rural facilities and critical access hospitals pay premiums because recruiting is difficult. A CRNA willing to work 13 weeks in rural Wyoming or Montana can earn $240/hour — $60,000 in a single quarter.
A staff CRNA at $210,000 W-2 has no choice but to pay taxes on gross income. A locum CRNA operating through their own LLC or S-Corp can deduct:
A locum CRNA earning $380,000 who runs through an S-Corp and maximizes retirement contributions can reduce taxable income to $280,000–$300,000, while a W-2 CRNA at $210,000 has no such flexibility. The effective tax rate difference can be 8–12 percentage points on a high income.
This is the most financially significant tax structure available to locum CRNAs and it's widely underused. As a self-employed individual, you can contribute:
A W-2 staff CRNA maxes out at $23,500 in their 403b. A locum CRNA can shelter $69,000 — nearly 3x as much. On a $380,000 gross income, that's an additional $45,500 going into tax-advantaged accounts per year vs. a staff peer. Over 10 years at 7% growth: $650,000+ in additional investment portfolio from the tax structure alone.
| Agency | Known For | CRNA-Specific Strength |
|---|---|---|
| CompHealth | Largest locum network | Wide hospital/surgery center inventory |
| Weatherby Healthcare | Premium placements | Strong rural + critical access placements |
| AMN Healthcare | Travel + locum hybrid | Integrated with travel nursing operations |
| Staff Care | Long-term assignments | Good for CRNAs wanting 6-month+ blocks |
| Locumstory | Rate transparency | Allows you to compare offers across agencies |
Always work with 2–3 agencies simultaneously. Agencies don't share exclusive contracts — the same facility often uses multiple agencies at different rates. Comparing offers is standard practice and not rude.
Before going fully locum: Build a 6-month expense reserve. Your first assignment gap, a contract cancellation, or a slower placement period shouldn't force you to take a bad assignment. Most CRNAs transition from staff to hybrid (some staff shifts + locum) before going fully locum.
The highest-earning CRNAs in the profession often run a hybrid model:
A CRNA working 36 hours/week at a staff position ($115/hr) plus 8 locum assignments/year at 40 hours each ($200/hr) can gross $280,000–$340,000 annually — significantly above a pure staff position — while maintaining the institutional connection most CRNAs want.
CRNA locum tenens is the clearest path to $300k+ in the profession for those with experience. The combination of premium per-diem rates, housing coverage, and self-employment tax advantages creates a financial structure that's significantly superior to W-2 employment for CRNAs who can handle variable income and minimal job security.
The two requirements: 2+ years of staff experience first, and a 6-month financial runway before your first gap. Build both, then move. The earning ceiling in this profession is much higher than most CRNAs realize.
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